LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs
LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs
LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs
LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs
LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs
LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs
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LEM Shiitake Mushroom Mycelia Extract | Premium Japanese Immune Support Supplement - 1.5g x 30 Packs

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$226.85 USD
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$226.85 USD
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Experience the power of Japan's most researched shiitake mushroom supplement. LEM (Lentinula Edodes Mycelia) extract represents over four decades of Japanese biotechnology innovation, delivering concentrated immune-supporting compounds in convenient daily sachets.

Unlike ordinary shiitake mushroom supplements that use only the fruiting body, this premium extract is derived from shiitake mycelia—the nutrient-dense "root system" where the mushroom's most potent bioactive compounds are concentrated. Through Noda Shokukin's proprietary extraction process, developed and refined since 1969, these beneficial compounds become bioavailable for maximum absorption.

Learn more about shiitake mushroom health benefits

Recommended For +
How It Works +

How LEM Supports Immune Function

The immune system relies on a complex network of cells, proteins, and signaling molecules working in coordination. Shiitake mushroom extract, particularly LEM, provides nutritional support for this system through multiple mechanisms.

Beta-Glucan Immune Modulation LEM contains beta-glucans, polysaccharides that interact with immune cells in the gut-associated lymphoid tissue (GALT). Research suggests these compounds help "train" immune cells, supporting appropriate immune responses without overstimulation.

Antioxidant Protection Oxidative stress can compromise immune cell function. LEM's lignin compounds and other antioxidants help protect cells from oxidative damage, supporting the integrity of immune tissues.

Gut-Immune Connection Approximately 70% of immune tissue resides in the gut. LEM's prebiotic-like compounds support the gut environment where much of immune system activity occurs.

Cellular Support Studies on LEM have examined its effects on natural killer (NK) cell activity and cytokine balance—key components of the body's surveillance and response systems.

The Complete Guide to Shiitake Mushroom Health Benefits

Direction For Use +
  1. Take 1 to 3 sachets daily as a dietary supplement.
  2. Consume in the morning or between meals for optimal absorption.
  3. Dissolve the fine powder in warm water or take directly with water.
  4. Consistent daily use is recommended for at least three months.
    Note: Do not exceed the recommended daily intake.
Ingredients +

Ingredients: Shiitake mushroom mycelia extract (LEM), lactose

Allergen Information:

  • Contains: Milk (lactose)
  • Free from: Gluten, soy, eggs, fish (sardine, anchovy), shellfish, nuts
Safety Information & Precautions +
  • Not recommended for individuals with a known allergy to mushrooms or lactose
  • Consult a physician if you are taking immunosuppressants or blood-thinning medications
  • Pregnant or nursing women should consult their doctor before using this supplement
  • Keep out of reach of children to prevent accidental choking or ingestion
  • Discontinue use immediately and consult a doctor if any adverse reactions occur
  • Consult your healthcare provider if you have an underlying medical condition
Product Specification +
  • Contents/Quantity: 30 sachets
  • Serving Size: 1 sachet (1.5g)
  • Servings Per Container: 30 servings
  • Net Weight: 45g (1.5g x 30)
  • Form: Fine granules (powder)
Manufacturer +

Noda Shokukin Kogyo Co., Ltd.

We looked beyond marketing claims to examine manufacturing heritage, extraction methods, and scientific backing. Noda Shokukin's LEM stood out for three reasons:

First, their 45+ year track record in mycelia extraction technology. While many supplement companies have only recently entered the mushroom market, Noda Shokukin pioneered LEM research in Japan during the 1970s and has continuously refined their process.

Second, the unique extraction method. Most shiitake supplements simply dry and powder the mushroom cap. LEM undergoes a four-month cultivation period followed by enzymatic extraction, releasing compounds like water-soluble lignin and specific polysaccharides that aren't accessible from the fruiting body alone.

Third, the extensive research backing. LEM has been the subject of published studies examining its effects on immune function, liver health, and cellular protection—research that many generic "mushroom complex" products simply cannot match.

FAQ

What exactly is LEM and how does it benefit me?
LEM stands for Lentinula Edodes Mycelia, a nutrient-rich extract from Shiitake mushroom "roots." It contains unique polysaccharides and lignin that provide superior immune and liver support compared to ordinary dried mushroom caps.
Can I take Shiikin along with my other medications?
While LEM is natural, we recommend consulting your physician if you are taking immunosuppressants or blood thinners. This ensures the supplement complements your specific medical regimen without any potential negative drug interactions.
What's the difference between LEM and AHCC?
Both LEM and AHCC are shiitake-derived supplements, but they differ in their source material, extraction process, and compound profiles. LEM is extracted from shiitake mycelia grown on solid medium, rich in beta-glucans and lignin compounds. AHCC (Active Hexose Correlated Compound) is derived from shiitake mycelia grown in liquid culture, emphasizing alpha-glucans with lower molecular weight. Both have been studied for immune support, with AHCC having more research specifically on immune cell activation. Some health-conscious consumers use both for complementary benefits. Learn more in our guide on shiitake mushroom health benefits.
Is LEM the same as regular shiitake mushroom supplements?
No, LEM (Lentinula Edodes Mycelia) extract is fundamentally different from standard shiitake supplements. Most shiitake products use dried and powdered fruiting bodies (the caps and stems). LEM is extracted from the mycelia—the underground network that absorbs nutrients before the visible mushroom forms. This difference matters because mycelia contain unique compounds like water-soluble lignin and specific polysaccharide patterns not found in significant amounts in the fruiting body. Additionally, LEM undergoes enzymatic extraction that makes these compounds bioavailable, while simple dried mushroom powder retains intact cell walls that limit absorption.
How long does it take to see results from shiitake mushroom supplements?
Results vary based on individual health status and what you're hoping to achieve. Many users report increased energy and improved sense of wellbeing within 2-4 weeks of consistent daily use. For immune support benefits, most research suggests that mushroom beta-glucans require consistent intake over 8-12 weeks to show measurable effects on immune markers. We recommend committing to at least 3 months of daily use before evaluating results. Keep in mind that supplements work best as part of overall healthy lifestyle practices including adequate sleep, nutrition, and stress management.
Why is this shiitake mushroom supplement more expensive than others I've seen?
The price reflects several factors that distinguish LEM from commodity mushroom supplements. First, the four-month cultivation period (versus weeks for standard products) significantly increases production time and costs. Second, the proprietary enzymatic extraction process requires specialized equipment and expertise developed over 45 years. Third, Noda Shokukin maintains Japanese GMP manufacturing standards with comprehensive testing protocols. Finally, the finished product contains concentrated bioactive compounds rather than simply dried mushroom powder. When evaluating cost, consider the daily price and compare the extraction quality rather than just price per gram.
What is the best way to store the sachets?
Store the sachets in a cool, dry place away from direct sunlight. The individual packaging protects the powder from moisture, making it convenient to take with you while maintaining maximum nutritional potency.
What does the fine powder taste like?
The fine powder has a mild, earthy mushroom flavor with a hint of sweetness from lactose. It dissolves easily in warm water or can be taken directly with a glass of water.