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SPIC Corporation

Lypo-C: Premium Japanese Vitamin C and D Supplement with Liposome Technology

Lypo-C: Premium Japanese Vitamin C and D Supplement with Liposome Technology

Japan's first domestically manufactured liposomal vitamin C and D supplement delivers 1,000mg Vitamin C and 2,000IU Vitamin D per packet using advanced 100nm liposome technology for efficient absorption.
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Regular price $79.98 USD
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Key Takeaways

Dual Vitamin Formula

Each packet delivers 1,000mg Vitamin C and 2,000IU Vitamin D3 combined in a single liposomal supplement for efficient nutrient delivery.

Advanced Liposome Technology

Uniform 100nm phospholipid capsules encapsulate water-soluble Vitamin C inside and fat-soluble Vitamin D within the membrane for optimal absorption.

Premium Quality Ingredients

Uses Q-C (Scotland-made Vitamin C) and Q-D (France-made Vitamin D3) from DSM, meeting strict manufacturing safety standards.

Clean Formula Commitment

Free from sweeteners, colorants, fragrances, and preservatives. Only essential ingredients for delivering vitamins effectively.

Best For

Those with limited sun exposure, office workers, people avoiding UV rays, and anyone seeking to efficiently supplement both essential vitamins together.

Award-Winning Recognition

Rakuten Vitamin D category #1 ranking with 718+ reviews. 21 Best Cosmetic Awards winner across Japanese beauty and fashion magazines.

Why It Works

Benefits

Lypo-C Vitamin C+D delivers two essential vitamins through Japan's proprietary liposome technology for efficient nutrient delivery.

1

Efficient Dual Vitamin Absorption

The proprietary Lypo-Capsule technology encapsulates water-soluble Vitamin C within the hydrophilic core and fat-soluble Vitamin D within the lipid bilayer of each phospholipid capsule. This allows both vitamins with different solubility properties to be absorbed together efficiently in a single supplement.

Liposome technology
2

Addresses Vitamin D Deficiency Concerns

Research from Tokyo Jikei Medical University indicates that 98% of Japanese adults may have insufficient vitamin D levels. Modern indoor lifestyles, UV-protective habits, and dietary changes contribute to this widespread deficiency. Each packet provides 2,000IU of Vitamin D3 to support adequate intake.

University research cited
3

Premium Ingredient Quality

Uses Q-C, a premium Vitamin C manufactured in Scotland by DSM, and Q-D, a wool-derived Vitamin D3 from France by DSM. Both ingredients meet DSM's strict self-imposed manufacturing safety standards including traceability and non-GMO verification.

DSM certified ingredients
4

Clean, Additive-Free Formula

Contains only essential ingredients: Vitamin C, lecithin (soy-derived), alcohol, sodium citrate, citric acid, and Vitamin D3. No sweeteners, colorants, fragrances, or preservatives are added. The natural seawater-like taste comes from the sodium used to stabilize the liposomes.

No unnecessary additives

The Science

How It Works

Understanding Lypo-C's proprietary liposome technology and why liquid form matters.

Liposome Technology: Two Vitamins in One Capsule

Liposome Technology: Two Vitamins in One Capsule

The phospholipid capsule structure mirrors human cell membranes.

Water-soluble Vitamin C is enclosed within the hydrophilic (water-loving) interior, while fat-soluble Vitamin D is embedded within the lipophilic (fat-loving) bilayer membrane.

This dual-compartment design allows both vitamins to be delivered together efficiently, taking advantage of each vitamin's natural properties.
Liquid Form Maintains Liposome Integrity

Liquid Form Maintains Liposome Integrity

Lypo-C is delivered in liquid form rather than powder because liposomes maintain their structure better in liquid state.

Converting liposomes to powder can damage many of the delicate capsule structures and cause size irregularities.

The liquid formulation preserves the uniform 100nm particle size that supports optimal absorption.
Uniform Nano-Size for Consistent Quality

Uniform Nano-Size for Consistent Quality

Each manufacturing batch is tested for particle size distribution. Only products with liposomes uniformly sized at approximately 100nm are released.

This consistency ensures stable liposome structures that disperse smoothly in water without separating or settling - a hallmark of Lypo-Capsule technology quality.

The Science

Research & Evidence

Data and research supporting the need for vitamin C and D supplementation.

Vitamin D Deficiency Statistics

Vitamin D Deficiency Statistics—A blood concentration study of approximately 5,500 Japanese adults published by Tokyo Jikei Medical University (June 5, 2023) found that 98% of participants had insufficient vitamin D levels.

Award Recognition

Award Recognition—Lypo-C products have received 21 Best Cosmetic Awards across Japanese fashion, beauty, and women's magazines in 2023-2024. The product is also recommended by the Japan Intravenous Therapy Association.

Advanced Liposome Technology

Advanced Liposome Technology—Secret 1 | Liquid Liposomes A raw state without alteration Lypo-C is the only domestically manufactured product with stabilization technology capable of packaging vitamin C liposomes in liquid form in pouches. Secret 2 | Nearly Uniform Size Efficiently delivers high concentration! Most liposomes are stable at an ultra-small size of approximately 100nm. Through stabilization technology that prevents them from growing larger over time, you can supplement with high-quality liposomes.

A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient Research Highlights

VITAMIN C

Vitamin C (ascorbic acid) is a water-soluble vitamin essential for collagen synthesis, antioxidant protection, and immune function. The body cannot produce Vitamin C and must obtain it from diet or supplements. Lypo-C uses Q-C from DSM, manufactured in Scotland with full traceability.

DSM ingredient specifications
VITAMIN D3

Vitamin D3 (cholecalciferol) is a fat-soluble vitamin important for calcium absorption and bone health. While the body can synthesize it from sunlight exposure, modern lifestyles often result in insufficient production. Lypo-C uses Q-D from DSM, derived from wool.

DSM specifications, Tokyo Jikei research
LIPOSOME TECHNOLOGY

Liposomes are microscopic spherical vesicles made of phospholipids, the same material as human cell membranes. They can encapsulate both water-soluble and fat-soluble substances. SPIC developed their Lypo-Capsule technology to create uniform 100nm liposomes.

SPIC official product information

About Brand Story

SPIC Corporation

SPIC Corporation

SPIC Corporation is a Japanese health supplement company based in Kamakura. In 2007, Dr. Atsuo Yanagisawa, a leading IV therapy authority, introduced high-dose vitamin C technology from the United States and partnered with SPIC to create a convenient, high-quality liposomal supplement for home use.

In 2014, SPIC developed its proprietary Lipo-Capsule Technology, and in January 2015 launched Lypo-Capsule Vitamin C—Japan's first domestically manufactured liposomal vitamin C supplement. In 2023, the company expanded with Lypo-Capsule Vitamin C+D, continuing its mission to deliver essential nutrients deep into the body.

Our Curation Process

Why We Selected This Product

Every product at Naturacare undergoes rigorous evaluation before joining our collection.

革新性

Innovation

Japan's first domestically manufactured liposomal Vitamin C+D supplement. SPIC pioneered the technology to create uniform 100nm liposomes in liquid form, a technical achievement in the supplement industry.

品質

Quality Assurance

Premium DSM ingredients (Q-C and Q-D) with full traceability. Manufactured in a GMP-certified facility in Japan. Clean formula with no unnecessary additives.

信頼性

Credibility

Recommended by Dr. Atsuo Yanagisawa, authority in IV vitamin therapy. 21 Best Cosmetic Awards. Rakuten #1 ranking with 718+ reviews. Brand heritage dating back to 2007.

Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.

We selected Lypo-C because it represents Japanese innovation at its finest - taking established science (liposome technology) and perfecting it with meticulous attention to quality, from ingredient sourcing to manufacturing processes.

Why Japan

The Japanese Advantage

Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.

Rigorous Quality Standards

Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.

GMP-Certified Manufacturing

All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.

Centuries of Tradition

Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.

Transparent Sourcing

Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.

Directions

How to Use

Simple daily routine for optimal nutrient support.

As a food supplement, take 1-3 packets daily.

Consume directly or mix with water or fruit juice.

Best taken on an empty stomach, such as before meals.

For those establishing a routine, taking before bedtime is recommended by the brand.

Tips for Best Results

  • Take on an empty stomach for optimal absorption
  • Do NOT mix with hot water above 60C (140F) as heat may affect liposome structure
  • Do NOT mix with oil-containing beverages or foods
  • Can be mixed with amazake (sweet rice drink) for enhanced gut support
  • Store in a cool, dry place away from direct sunlight and heat
  • Individual packets are convenient for travel and on-the-go use

What's Inside

Ingredients

Clean formula with premium sourced vitamins and minimal ingredients.

1,000mg

Vitamin C

Q-C from DSM (Scotland-made), essential for collagen synthesis and antioxidant protection

2,000IU (50μg)

Vitamin D3

Q-D from DSM (France-made, wool-derived), supports calcium absorption and bone health

100nm

Liposome Size

Soy-derived lecithin phospholipid capsules for efficient vitamin delivery

Ingredients: Vitamin C (manufactured in UK), Lecithin (soy-derived), Alcohol, Sodium citrate, Citric acid, Vitamin D3

Allergen Information: Contains: Soy (from lecithin). Does NOT contain: Sweeteners, Colorants, Fragrances, Preservatives.

Important Information

Safety & Precautions

Please read before use.

Allergies

Contains soy-derived lecithin. Not suitable for those with soy allergies.

Pregnancy & Nursing

Consult your healthcare provider before use if you are pregnant, nursing, or planning to become pregnant.

Medications

If you take prescription medications, consult your doctor before starting this supplement.

Dosage

The recommended intake is 1-3 packets per day. Do not exceed 3 packets daily. Vitamin D is fat-soluble and can accumulate in the body.

Taste

The product has a seawater-like taste with some bitterness due to the sodium used to stabilize the liposomes and Vitamin C. This is normal.

Disclaimer

This is a dietary supplement, not a medicine. It supports wellness but does not treat, cure, or prevent any disease.

Storage

Store in a cool, dry place away from direct sunlight and heat. Once opened, consume promptly.

Details

Product Specifications

Product Name
Lypo-Capsule Vitamin C+D
Brand
SPIC / Lypo-C
Contents
186g (6.2g x 30 packets)
Serving Size
1-3 packets
Servings Per Container
30 servings (at 1 packet/day)
Net Weight
186g
Form
Liquid (individual packets)
Country of Origin
Japan
Manufacturing
SPIC Co., Ltd. (GMP-certified facility)

Questions

Frequently Asked Questions

Yes, you can take vitamin C and D together. In fact, Lypo-C is specifically designed to deliver both vitamins in a single packet.

The liposome technology encapsulates water-soluble Vitamin C inside the capsule and fat-soluble Vitamin D within the lipid membrane, allowing efficient co-delivery of both nutrients.
Lypo-C uses proprietary liposome technology that encapsulates vitamins in phospholipid capsules similar to human cell membranes.

The liquid formula maintains uniform 100nm particle size for consistent quality. Unlike powder or tablet forms, the liposomes are preserved in their optimal state.
According to Tokyo Jikei Medical University research, factors include: dietary changes reducing vitamin D-rich food consumption, Japanese beauty culture's emphasis on UV avoidance, and modern indoor lifestyles including remote work.

These factors limit both dietary intake and sun-dependent synthesis of vitamin D.
Each 6.2g packet contains 1,000mg of Vitamin C and 50mcg (2,000IU) of Vitamin D3.

The Vitamin C is Q-C manufactured in Scotland by DSM, and the Vitamin D3 is Q-D manufactured in France by DSM from wool sources.
The seawater-like taste comes from the sodium citrate used to stabilize the liposome structure and Vitamin C.

Because Lypo-C contains no sweeteners, colorants, or artificial flavors, you taste the natural characteristics of the essential ingredients.
Take on an empty stomach for optimal absorption, such as before meals.

For building a consistent habit, the brand recommends taking it before bed. Any time of day is acceptable as this is a food supplement.
No. The Vitamin D3 (Q-D) is derived from wool (sheep's lanolin), making it unsuitable for vegans.

The product also contains soy-derived lecithin, which is suitable for vegetarians but not those with soy allergies.
Lypo-C has received 21 Best Cosmetic Awards from Japanese fashion, beauty, and women's magazines in 2023-2024.

It achieved #1 ranking in Rakuten's Vitamin D category and is recommended by the Japan Intravenous Therapy Association.