Key Takeaways
Salacinol Power
Contains Salacinol from Salacia, a tropical plant traditionally used by royalty. This key ingredient blocks sugar-digesting enzymes in the small intestine, reducing sugar absorption.
Simple Daily Routine
Take 8 tablets daily, split into 2-4 tablets before each meal with water. Small tablet size makes them easy to swallow consistently.
4 Certified Functions
Functional Food (機能性表示食品) registration D677 with four scientifically-validated functions backed by clinical trials and research reviews.
Japanese Pharmaceutical Heritage
Developed by FUJIFILM using their advanced stabilization technology. Patented in Japan and US for stable, high-concentration Salacia extraction.
Best For
Those with BMI 25-30 seeking natural blood sugar support, fat absorption control, and belly fat reduction without stimulants.
Market Leader
#1 Salacia supplement manufacturer in Japan. Metabarrier series has sold over 15 million units. Rakuten Daily Ranking #1 in Salacia category.
Is This Right For You?
Recommended For
Metabarrier Premium EX is FUJIFILM's premium blood sugar support supplement designed for those seeking comprehensive metabolic wellness support.
If you're concerned about blood sugar levels after meals and want natural support from clinically-validated ingredients
If you love fried foods, rich dishes, and sweets but want to manage their impact on your waistline
If you've noticed your BMI creeping up and want a scientifically-backed approach to reducing belly fat
If you're looking for a comprehensive sugar blocker supplement that also supports gut health
If you want to understand what the best supplement for blood sugar really looks like with transparent clinical data
If you're searching for premium salacia reticulata extract from a trusted pharmaceutical company
If you've tried various blood sugar control supplements but want one backed by multiple clinical trials
If you're seeking blood sugar natural supplements that work through multiple mechanisms, not just one
Why It Works
Benefits
Metabarrier Premium EX delivers comprehensive metabolic support through four clinically-validated functions.
Blocks Sugar Absorption
Salacinol, derived from Salacia, inhibits the digestive enzymes in your small intestine that break down sugars. When these enzymes are blocked, sugars cannot be properly digested and absorbed into your bloodstream. This helps maintain healthy blood sugar levels after meals, especially important for those who enjoy carbohydrate-rich foods.
Research-reviewedSuppresses Fat Absorption
The comprehensive formula in Metabarrier Premium EX works to inhibit fat-digesting enzymes, reducing the amount of dietary fat your body absorbs from meals. Clinical trials showed significant reduction in blood triglyceride levels after high-fat meals compared to placebo.
Clinical trial provenImproves Gut Environment
Continuous intake of Salacinol increases beneficial Bifidobacteria in your intestines. Research showed approximately 5x increase in Bifidobacteria ratio after 4 weeks of daily use. A healthy gut environment supports overall metabolic wellness and digestion.
Research-reviewedReduces Belly Fat & BMI
For those with BMI 25-30, clinical trials demonstrated that 8 weeks of continuous use reduced body weight (~1.1kg), waist circumference (~1.1cm), and total fat area (~26cm2) compared to placebo. This comprehensive approach helps reduce elevated BMI through multiple pathways.
Clinical trial provenThe Science
How It Works
Understanding the science behind Metabarrier Premium EX's four-function approach.
Sugar Absorption Inhibition
When these enzymes are blocked, sugars cannot be properly digested and pass through without being absorbed into your bloodstream. This mechanism has been validated through systematic research reviews of clinical studies on Salacinol.
Gut Environment Improvement
A 4-week clinical study with 30 healthy adult males showed that the Salacinol group experienced approximately 5x increase in Bifidobacteria ratio compared to placebo. This improved gut environment supports overall digestive health and metabolic function.
Fat Absorption Suppression & BMI Reduction
An 8-week clinical trial with 45 subjects (BMI 25-30) demonstrated comprehensive improvements:
- Body weight: ~1.1kg reduction vs placebo
- Waist circumference: ~1.1cm reduction
- Total fat area: ~26cm2 reduction
The Science
Research & Evidence
Metabarrier Premium EX is backed by multiple clinical trials and research reviews supporting its four certified functions.
Body Composition Clinical Trial (8 Weeks)—45 subjects with BMI 25-30, randomized to Metabarrier Premium EX or placebo for 8 weeks. Results showed ~1.1kg weight reduction, ~1.1cm waist reduction, ~26cm2 fat area reduction vs placebo. Source: Seki et al., Pharmacology and Therapeutics, 45, 957-966 (2017)
Bifidobacteria Increase Study (4 Weeks)—30 healthy adult males, randomized to Salacinol (1.0mg/day) or placebo for 4 weeks. Salacinol group showed approximately 5x increase in Bifidobacteria ratio. Source: Oda Y. et al., PLOS ONE. 10(12), e0142909, 2015
Waist Circumference Reduction—Clinical trial graph showing waist circumference changes over 8 weeks. Metabarrier Premium EX group showed ~1.1cm greater reduction compared to placebo group.
Fat Area Reduction Results—Total fat area (visceral + subcutaneous) reduction of approximately 26cm2 greater than placebo after 8 weeks of continuous use in subjects with BMI 25-30.
A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.
Consumer Validation
#1 SALACIA MANUFACTURER
Based on H&B Foods Marketing Report 2021, FUJIFILM is the #1 Salacia supplement manufacturer in Japan by sales performance. The Metabarrier series has established itself as the market leader in the blood sugar support category.
H&B Foods Marketing Report15+ MILLION UNITS SOLD
The Metabarrier series has sold over 15 million units since its launch in April 2008. This cumulative sales figure demonstrates sustained consumer trust over more than 15 years in the Japanese market.
FUJIFILM sales data (2008-2021)RAKUTEN RANKING #1
Metabarrier Premium EX achieved #1 Daily Ranking in the Salacia category on Rakuten, Japan's largest e-commerce platform. This ranking reflects real consumer purchasing behavior and product satisfaction.
Rakuten Daily Ranking (April 2025)The Story
About Brand Story
FUJIFILM Healthcare Laboratory Co., Ltd.
Their flagship ASTALIFT brand features nano-formulated astaxanthin identified from 4,000+ antioxidant compounds, while Metabarrier supplements have achieved Japan's No.1 market position in the salacia category for seven consecutive years. This represents FUJIFILM's successful transformation — proving that while business models may expire, core technologies endure.
Our Curation Process
Why We Selected This Product
Every product at Naturacare undergoes rigorous evaluation before joining our collection.
革新性
Innovation
FUJIFILM applied their advanced film stabilization technology to create a patented method for extracting and stabilizing Salacinol from Salacia. This innovation solved the challenge of Salacia's instability in water, enabling high-concentration, consistent tablets.
信頼性
Reliability
Backed by multiple clinical trials published in peer-reviewed journals, not just ingredient studies. The Functional Food registration (D677) requires submission of scientific evidence to Japan's Consumer Affairs Agency.
実績
Proven Track Record
Over 15 million units sold in the Metabarrier series since 2008. #1 Salacia manufacturer in Japan. This isn't an unproven newcomer - it's Japan's leading blood sugar support supplement line.
Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.
We selected Metabarrier Premium EX because it represents the pinnacle of Japanese supplement science: pharmaceutical-grade manufacturing from FUJIFILM, four clinically-validated functions, and a decade-plus track record of consumer trust.
Why Japan
The Japanese Advantage
Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.
Rigorous Quality Standards
Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.
GMP-Certified Manufacturing
All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.
Centuries of Tradition
Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.
Transparent Sourcing
Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.
Directions
How to Use
Proper usage ensures optimal results from your blood sugar support supplement.
Tips for Best Results
- Take tablets 15-30 minutes before meals for optimal enzyme inhibition timing
- Use consistently with all meals, especially those high in carbohydrates or fats
- For larger, richer meals, take 3-4 tablets; for lighter meals, 2 tablets is sufficient
- Combine with balanced nutrition and moderate exercise for comprehensive metabolic support
- Allow 4-8 weeks of consistent use for body composition benefits to become noticeable
- Store in a cool, dry place away from direct sunlight; keep the bag sealed after opening
What's Inside
Ingredients
Functional ingredients with clearly disclosed amounts per daily serving (8 tablets).
Salacinol
Active compound from Salacia that inhibits sugar-digesting enzymes in the small intestine
Difficult-to-digest Dextrin
Dietary fiber supporting digestive health and gut function
Epigallocatechin Gallate
Green tea catechin with metabolic support properties
Ingredients: Difficult-to-digest dextrin (dietary fiber) (manufactured in USA), Salacia concentrated extract, Red wine polyphenols, Seaweed extract, Hihatsu extract, Chromium-containing yeast / Crystalline cellulose, Green tea extract, Calcium carbonate, Calcium stearate, Fine silicon dioxide, Glazing agent, Enzyme-treated rutin, Spice extract
Allergen Information: Contains: None of the 28 designated allergens. Free From: Major allergens (eggs, milk, wheat, shrimp, crab, buckwheat, peanuts)
Important Information
Safety & Precautions
Please read before use.
Allergies
Review the ingredient list carefully. Although this product does not contain any of the 28 designated allergens, discontinue use if you experience any allergic reactions.
Pregnancy & Nursing
This product is not developed for pregnant women (including those planning pregnancy) or nursing mothers. Please refrain from use during pregnancy and breastfeeding.
Medications
If you are taking prescription medications, especially diabetes medications, consult your doctor before use. If you are currently under medical treatment, please consult your healthcare provider.
Dosage
The recommended daily amount is 8 tablets. Divide into 2-4 tablets per meal, 3 times daily. Do not exceed the recommended amount. Be mindful of excessive fat intake and combine with moderate exercise.
Children
This product is not developed for minors. Please keep out of reach of children.
Medical Conditions
This product is not developed for those with existing medical conditions. If you have any health conditions, consult your physician before use. If you experience any unusual symptoms, discontinue use immediately and consult a doctor.
Disclaimer
This is a Functional Food, not a medicine. It is intended to support wellness but is not meant to diagnose, treat, cure, or prevent any disease. Maintain a balanced diet with proper portions of staple foods, main dishes, and side dishes.
Storage
Store in a cool, dry place away from direct sunlight and high humidity. After opening, close the zipper securely and consume promptly.
Details
Product Specifications
Questions
Frequently Asked Questions
Unlike many supplements with vague claims, this product has Functional Food certification (D677) requiring scientific evidence submission.
When blocked by Salacinol, sugars cannot be properly digested and pass through without being absorbed into your bloodstream.
FUJIFILM's patented extraction and stabilization technology ensures consistent, high-concentration delivery of this beneficial compound in every tablet.
Take 2-4 tablets before each meal, totaling 8 tablets daily.
After 8 weeks of use in those with BMI 25-30, subjects showed significant reductions in weight, waist, and fat area. Individual results vary.
The product also contains dietary fiber (difficult-to-digest dextrin), green tea catechins, and seaweed-derived phlorotannins - all natural ingredients supporting metabolic wellness.
Both may affect blood sugar levels, and your healthcare provider should monitor your response and potentially adjust your medication dosage accordingly.
For body composition changes (weight, waist circumference, fat area), the clinical trial demonstrated measurable results at 8 weeks of continuous use.
The Metabarrier series has been sold for over 15 years with over 15 million units distributed. However, if you experience any adverse effects, discontinue use and consult a healthcare provider.
Beware of counterfeit products on unauthorized marketplaces that may not contain proper ingredients or meet safety standards.