Key Takeaways
High-Potency Formula
4000FU of nattokinase per daily serving (4 capsules), one of the highest concentrations available in Japanese natto supplements.
Easy Daily Routine
Take 4 odorless, tasteless capsules daily with water. Convenient soft capsule form makes it easy to get natto's benefits.
Advanced Capsule Technology
High-dispersion and acid-resistant capsules help protect nattokinase from stomach acid, delivering nutrients to the intestines.
Trusted Japanese Heritage
From Noguchi Medical Research Institute, established in 1953. Over 40 years of supplement expertise with 1,000,000+ units shipped.
Best For
Those who enjoy oily foods, have irregular eating habits, busy lifestyles, or want natto's circulation benefits without eating fermented soybeans.
Developed by Nutrition Expert
Formulated by a registered dietitian as part of Noguchi's health supplement series. Made in a certified domestic factory in Japan.
Is This Right For You?
Recommended For
This natto supplement is designed for those seeking natural support for healthy blood circulation without eating traditional natto.
If you enjoy oily or rich foods and want to support your cardiovascular health naturally
If you have irregular eating habits and want to supplement your diet with circulation-supporting nutrients
If you lead a busy, stressful lifestyle and want to support your body's natural blood flow
If you dislike the taste, smell, or texture of natto but want its health benefits
If you're looking for a high-potency nattokinase supplement with 4000FU per serving
If you want a Japanese natto supplement from a trusted research institute with decades of experience
If you prefer capsules over powder or eating fermented foods for circulation support
If you're seeking a nattokinase supplement with vitamin K removed for compatibility with certain medications
Why It Works
Benefits
Noguchi Nattokinase HQ delivers the circulation-supporting benefits of traditional Japanese natto in a convenient, high-potency capsule form.
Supports Healthy Blood Circulation
Nattokinase is an enzyme derived from natto, the traditional Japanese fermented soybean food. This enzyme has been studied for its potential to support healthy blood flow and circulation. Noguchi Nattokinase HQ provides 4000FU per daily serving.
Traditional Japanese ingredientConvenient Alternative to Eating Natto
Many people want the health benefits of natto but find the taste, smell, or sticky texture off-putting. Noguchi Nattokinase HQ delivers nattokinase in odorless, tasteless soft capsules for easy daily use.
Easy-to-take capsule formAdvanced Absorption Technology
The supplement uses high-dispersion capsules that spread nutrients effectively in the stomach, combined with acid-resistant technology that helps protect the nattokinase enzyme from harsh stomach acid.
High-dispersion + acid-resistant capsulesComplementary Ingredients for Wellness
Beyond nattokinase, the formula includes onion skin extract (containing quercetin), brewer's yeast, and black pepper extract. These complementary ingredients support the overall circulation-supporting benefits.
Multi-ingredient formulaThe Science
How It Works
Understanding how nattokinase supports your body's natural circulation processes.
Nattokinase: The Power of Fermentation
When natto is made using Bacillus subtilis bacteria, this enzyme is created in the sticky, stringy part of the fermented beans.
Key benefits:
- Supports smooth blood flow
- Provides 4000FU (Fibrinolytic Units) per daily serving
- Derived from traditional Japanese fermented food
Advanced Capsule Delivery System
High-dispersion capsules ensure that after dissolution, the nutrient particles spread easily throughout the digestive system.
Acid-resistant coating helps protect the delicate nattokinase enzyme from stomach acid, allowing more of the active ingredient to reach the intestines where absorption occurs.
The Science
Research & Evidence
What we know about nattokinase and the quality behind this supplement.
Manufacturer Credibility—Noguchi Medical Research Institute has been developing health supplements for over 40 years, with cumulative shipments of over 1,000,000 units across the product series.
A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.
Ingredient Research Highlights
NATTOKINASE
Nattokinase is a serine protease enzyme with fibrinolytic activity. It has been the subject of research regarding blood flow and circulation support. The enzyme activity is measured in FU (Fibrinolytic Units).
Traditional Japanese fermented food researchQUERCETIN (from Onion Skin Extract)
Onion skin contains quercetin, a flavonoid with antioxidant properties. Quercetin has been studied for its potential cardiovascular benefits.
Plant flavonoid researchCONSUMER VALIDATION
Noguchi Medical Research Institute's supplement series has achieved cumulative shipments of over 1,000,000 units in Japan. The Nattokinase HQ product is part of their premium HQ (High Quality) line.
Manufacturer dataThe Story
About Brand Story
Noguchi Medical Research Institute (NMRI)
The company provides beauty and health-related products and services, with profits supporting international medical education programs for doctors, nurses, pharmacists, and dietitians noguchi-co through the U.S. foundation. Under the philosophy of "Humanity and Empathy in Medicine," Noguchi-co it cultivates healthcare professionals who can empathize with patients' pain and suffering. Headquartered in Toranomon, Tokyo.
Our Curation Process
Why We Selected This Product
Every product at Naturacare undergoes rigorous evaluation before joining our collection.
高配合
High Potency
With 4000FU of nattokinase per daily serving, this is among the highest-potency natto supplements available from a trusted Japanese manufacturer.
信頼性
Reliability
Noguchi Medical Research Institute has been in the health supplement business for over 40 years, with a track record of quality products developed by nutrition professionals.
技術革新
Technical Innovation
The combination of high-dispersion and acid-resistant capsule technology shows thoughtful formulation designed to maximize delivery of nattokinase.
Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.
We selected Noguchi Nattokinase HQ because it represents the best of Japanese supplement craftsmanship: high potency, trusted heritage, and thoughtful formulation.
Why Japan
The Japanese Advantage
Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.
Rigorous Quality Standards
Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.
GMP-Certified Manufacturing
All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.
Centuries of Tradition
Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.
Transparent Sourcing
Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.
Directions
How to Use
Simple daily routine for optimal results.
The capsules can be taken all at once or split throughout the day based on your preference.
Maintain consistent daily use for best results.
Tips for Best Results
- Take at a consistent time each day to build a routine
- Can be taken with or without food
- Store in a cool, dry place away from direct sunlight and heat
- Close the bottle cap tightly after opening
- Consume promptly after opening for maximum freshness
- Stay hydrated throughout the day
What's Inside
Ingredients
Quality Japanese ingredients with full transparency.
Nattokinase
Fibrinolytic enzyme from fermented soybeans (Vitamin K removed)
Onion Skin Extract
Contains quercetin, a flavonoid antioxidant
Brewer's Yeast
Nutritional yeast with B-vitamins and minerals
Ingredients: Flaxseed oil (manufactured in Belgium), Nattokinase-containing natto bacteria culture extract (soy flour, maltodextrin), Starch, Onion skin extract, Brewer's yeast, Black pepper extract, Gelatin, Glycerin, Emulsifier, Thickening polysaccharide, Cacao color (contains soy and gelatin)
Allergen Information: Contains: Soy, Gelatin. Does NOT contain: Vitamin K (removed from nattokinase).
Important Information
Safety & Precautions
Please read before use.
Allergies
Check the ingredient list if you have allergies. This product contains soy and gelatin.
Pregnancy & Nursing
If you are pregnant, nursing, or planning to become pregnant, consult your healthcare provider before use.
Medications
If you are receiving medical treatment or taking medications (especially blood thinners), consult your doctor before starting this supplement.
Dosage
The recommended amount is 4 capsules per day. Do not exceed the recommended daily amount.
Children
This product is intended for adults. Keep out of reach of children.
Storage
Store in a cool, dry place away from direct sunlight, heat, and humidity. Keep the bottle tightly closed after opening.
Details
Product Specifications
Questions
Frequently Asked Questions
Nattokinase has been studied for its potential to support healthy blood flow. This supplement delivers 4000FU of nattokinase per serving in an easy-to-take capsule form.
Pregnant and nursing women should also seek medical advice before use.
This supplement has vitamin K removed from the nattokinase.
Consistency is more important than expecting immediate results.
Noguchi Nattokinase HQ provides 4000FU per serving and comes from a manufacturer with over 40 years of experience.
This Noguchi Nattokinase HQ is made by the Noguchi Medical Research Institute, a respected name with decades of expertise.
The enzyme supports smooth blood flow, which is particularly relevant for those with sedentary lifestyles, irregular diets, or who consume oily foods.
This supplement uses acid-resistant capsules that help deliver the enzyme to the intestines for better absorption.