ORIHIRO Co., Ltd.

Japanese Nattokinase 4000: Premium Blood Circulation Support Supplement

Authentic Japanese nattokinase supplement with 4000FU enzyme activity per serving, equivalent to 2 packs of natto. Enhanced with DHA, EPA, DPA, and Vitamin E to support healthy blood flow and circulation.

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$45.98 USD

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Potent Nattokinase Formula

Each daily serving of 2 capsules delivers 4000FU of nattokinase activity, equivalent to eating approximately 100g (2 packs) of fermented natto.

Convenient Daily Routine

Just 2 easy-to-swallow soft capsules per day with water. No natto smell or sticky texture to deal with.

Quality Assured

Manufactured in Japan by ORIHIRO, a trusted supplement company. Soft capsule form eliminates the characteristic natto odor.

Traditional Japanese Wellness

Nattokinase is an enzyme unique to natto, created during the fermentation process. Part of Japanese dietary tradition for centuries.

Best For

Those who want nattokinase benefits but dislike natto's taste, smell, or texture, or cannot eat it daily due to lifestyle constraints.

Enhanced Formula

Beyond nattokinase, includes 7 carefully selected supporting ingredients: DHA, EPA, DPA, Rutin, Hesperidin, Lecithin, and Vitamin E.

If you're concerned about maintaining healthy blood flow but struggle to eat natto regularly due to its taste or texture

If you've been looking for an authentic Japanese nattokinase supplement with verified activity levels

If you're busy with work and often experience stress, and want to support your cardiovascular wellness naturally

If you eat out frequently and worry about the effects of an irregular diet on your circulation health

If you want the benefits of natto but find the smell and sticky texture unpleasant

If you're looking for a convenient way to incorporate traditional Japanese fermented food benefits into your routine

If you lack regular exercise due to a busy lifestyle and want to support your overall health

If you're seeking a supplement that combines nattokinase with complementary ingredients like DHA, EPA, and Vitamin E

1

Supports Healthy Blood Circulation

Nattokinase is a fibrinolytic enzyme produced during natto fermentation. This unique enzyme supports healthy blood flow by helping to maintain normal fibrin levels in the blood. Each serving provides 4000FU of nattokinase activity for optimal support.

Traditional Japanese ingredient

2

Convenient Natto Alternative

Many people want nattokinase benefits but cannot tolerate natto's strong smell or sticky texture. ORIHIRO Nattokinase 4000 delivers the same active enzyme in odorless soft capsules, making daily supplementation easy and enjoyable.

Consumer-validated convenience

3

Comprehensive Omega-3 Support

In addition to nattokinase, this formula includes DHA (85mg), EPA (9mg), and DPA (2mg) from fish oil. These omega-3 fatty acids are known for their role in supporting cardiovascular health and complement nattokinase's circulation-supporting properties.

Research-backed ingredients

4

Synergistic Ingredient Blend

ORIHIRO has carefully selected 7 additional ingredients to enhance the formula: DHA, EPA, DPA, Rutin, Hesperidin (polyphenols), Lecithin (phospholipid), and Vitamin E (5.0mg, 79% daily value). This comprehensive blend supports overall wellness.

Enhanced formulation

What is Nattokinase?

Nattokinase is an enzyme that forms in the sticky, stringy portion of natto during the fermentation process.

Key characteristics:

Produced by Bacillus subtilis (natto bacteria)
Found exclusively in natto
Has fibrinolytic (fibrin-dissolving) properties

Concentrated Natto Power

ORIHIRO Nattokinase 4000 concentrates the nattokinase activity from approximately 100g of natto (about 2 packs) into just 2 soft capsules.

This provides:

4000FU (Fibrin Units) of enzyme activity per daily serving
Eliminates natto's characteristic smell and texture
Preserves the active enzyme in convenient form

Enhanced with 7 Supporting Ingredients

Beyond nattokinase, ORIHIRO has added seven carefully selected ingredients:

DHA, EPA, and DPA (omega-3 fatty acids from fish oil)
Rutin and Hesperidin (polyphenols)
Lecithin (a phospholipid)
Vitamin E (antioxidant support)

Ingredient Profile—ORIHIRO Nattokinase 4000 contains nattokinase (4000FU activity) plus DHA (85mg), EPA (9mg), DPA (2mg), Rutin (8mg), Hesperidin (4mg), Lecithin (10mg), and Vitamin E (5.0mg). All amounts clearly disclosed per daily serving.

A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient Research Highlights

NATTOKINASE

Nattokinase is a serine protease enzyme discovered in natto by Dr. Hiroyuki Sumi in the 1980s. It has been extensively studied for its fibrinolytic properties. The enzyme is measured in Fibrin Units (FU), with 2000FU being a commonly recommended daily intake.

Nattokinase research, Japanese fermented food science

DHA, EPA & DPA

These omega-3 fatty acids from fish oil are well-researched for cardiovascular health support. DHA and EPA in particular have been studied for their roles in maintaining healthy triglyceride levels and supporting overall heart health.

Omega-3 fatty acid research

VITAMIN E

Vitamin E is a fat-soluble antioxidant that helps protect cells from oxidative stress. The 5.0mg in this formula provides 79% of the nutritional standard value for adults.

Nutritional research

The Story

About Brand Story

ORIHIRO Co., Ltd.

ORIHIRO stands out by uniquely combining decades of health food expertise with advanced proprietary packaging technology. Based in Gunma, we leverage this engineering precision to create supplements that are exceptionally safe, ensuring ingredients remain potent and pure from factory to home.

We strictly adhere to international quality standards, including FSSC 22000 certification. By managing high-tech production lines ourselves, we guarantee reliability in every package. ORIHIRO is dedicated to supporting your vitality with products you can trust completely.

伝統

Tradition

Nattokinase comes from natto, a traditional Japanese fermented food with centuries of history. We value products that bring authentic Japanese wellness traditions to international customers.

利便性

Convenience

Not everyone can eat natto daily due to its unique taste and texture. This supplement delivers nattokinase benefits in an easy, odorless soft capsule form that fits any lifestyle.

信頼性

Reliability

ORIHIRO is a trusted Japanese supplement manufacturer. Their nattokinase product clearly discloses 4000FU activity and includes complementary ingredients for comprehensive support.

Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.

We selected ORIHIRO Nattokinase 4000 because it authentically delivers traditional Japanese nattokinase in a convenient modern format. For those who cannot eat natto regularly, this supplement offers a practical way to incorporate this unique enzyme into daily wellness routines.

Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.

Rigorous Quality Standards

Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.

GMP-Certified Manufacturing

All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.

Centuries of Tradition

Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.

Transparent Sourcing

Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.

Learn more

Take 2 soft capsules daily with water or warm water.

If you experience any throat discomfort, drink extra water.

Do not exceed the recommended daily amount. The capsules can be taken at any time of day that fits your routine.

Tips for Best Results

Take consistently at the same time each day to build a routine
Swallow capsules whole with plenty of water
Store in a cool, dry place away from direct sunlight
Keep the bottle cap tightly closed after opening; store in the outer box
Record the opening date on the package for freshness tracking
Best used as part of a balanced diet with proper nutrition

200mg (4000FU)

Nattokinase Cultured Extract

Fermented enzyme from natto bacteria with verified activity level

85mg

DHA

Omega-3 fatty acid from fish oil for cardiovascular support

5.0mg (79% DV)

Vitamin E

Fat-soluble antioxidant for cellular protection

Ingredients: Natto bacteria cultured extract powder (dextrin, natto bacteria cultured extract (contains soybean)) (manufactured in Taiwan), DHA-containing refined fish oil, safflower oil, GABA, Vitamin E-containing vegetable oil / modified starch, glycerin, gelling agent (thickening polysaccharide), emulsifier, beeswax, lecithin, rutin, cacao pigment, hesperidin

Allergen Information: Contains: Soybean. Does NOT contain: Egg, Milk, Wheat, Shrimp, Crab, Buckwheat, Peanut, or other major allergens (28 items per Japanese food labeling law).

Allergies

This product contains soybean. Not suitable for those with soybean allergies. Check the full ingredient list if you have any food sensitivities.

Pregnancy & Nursing

Not specified. Consult your healthcare provider before use if you are pregnant, nursing, or planning to become pregnant.

Medications

If you are receiving medical treatment, consult your physician before taking this supplement. Nattokinase may interact with blood-thinning medications.

Dosage

The recommended daily amount is 2 capsules. Do not exceed the recommended daily intake.

Children

Please refrain from giving this product to small children.

Discontinue Use

Rarely, this product may not suit your constitution. If you feel unwell, temporarily discontinue use.

Storage

Store in a cool, dry place away from direct sunlight, heat, and humidity. After opening, close the cap tightly, store in the outer box, and consume promptly.

Product Name

Japanese Nattokinase 4000: Premium Blood Circulation Support Supplement

Brand

ORIHIRO

Contents

60 soft capsules

Serving Size

2 capsules (970mg)

Servings Per Container

30 servings

Net Weight

29.1g (485mg x 60 capsules)

Form

Soft gel capsule

Country of Origin

Japan

Manufacturing

ORIHIRO Plandue Co., Ltd.

What is Japanese natto good for?

Natto is a traditional Japanese fermented soybean food known for its unique nutritional profile. It contains nattokinase, an enzyme produced during fermentation, along with protein, vitamin K2, and other nutrients.

Japanese people have consumed natto for centuries as part of a balanced diet. The nattokinase enzyme in particular has been studied for its role in supporting healthy blood circulation.

Do Japanese take nattokinase?

Yes, nattokinase supplements are popular in Japan, particularly among those who want the enzyme's benefits but cannot eat natto daily due to its strong smell and sticky texture.

ORIHIRO Nattokinase 4000 is designed specifically for this purpose, delivering 4000FU of nattokinase activity in convenient, odorless soft capsules.

Why don't doctors recommend nattokinase?

Some doctors may be cautious about nattokinase due to its fibrinolytic (fibrin-dissolving) properties, which could potentially interact with blood-thinning medications.

If you take anticoagulants or have bleeding disorders, consult your healthcare provider before use. For healthy individuals, nattokinase supplements can be part of a wellness routine.

What is another name for nattokinase?

Nattokinase is sometimes referred to as 'subtilisin NAT' or 'natto enzyme.' It belongs to the serine protease enzyme family.

The name 'nattokinase' comes from 'natto' (the fermented soybean food) and 'kinase' (though technically it's a protease, not a kinase).

What are the health benefits of Japanese nattokinase supplements?

Japanese nattokinase supplements like ORIHIRO Nattokinase 4000 are primarily taken to support healthy blood circulation. The enzyme has fibrinolytic properties that help maintain normal fibrin levels.

Many users appreciate being able to get nattokinase benefits without eating natto daily. This product also includes DHA, EPA, and Vitamin E for additional cardiovascular support.

Where can I buy authentic Japanese nattokinase products online?

Authentic Japanese nattokinase supplements can be purchased through Naturacare.jp, which specializes in curating genuine Japanese health products for international customers.

We source directly from trusted Japanese manufacturers like ORIHIRO to ensure authenticity. Look for products that clearly state nattokinase activity in FU (Fibrin Units).

Can I find Japanese nattokinase supplements with third-party quality testing?

ORIHIRO Nattokinase 4000 is manufactured in Japan by ORIHIRO Plandue Co., Ltd., a reputable company with established quality standards.

The product clearly discloses its nattokinase activity (4000FU at manufacture) and all ingredient amounts. When choosing any Japanese nattokinase supplement, look for transparent labeling.

How do I choose the best Japanese nattokinase supplement for blood circulation?

When selecting a Japanese nattokinase supplement, consider: nattokinase activity level (measured in FU - 2000-4000FU daily is common), form (soft capsules mask natto odor), additional supporting ingredients, and manufacturer reputation.

ORIHIRO Nattokinase 4000 meets all these criteria with 4000FU activity and 7 complementary ingredients.

Japanese Nattokinase 4000: Premium Blood Circulation Support Supplement