Shinya Koso Co., Ltd.

Night Diet Enzyme GOLD+: Japanese Metabolism Booster Supplement with 680 Living Enzymes

Japan's best-selling enzyme supplement with 22 million units sold worldwide. 680mg of living enzymes support metabolism of carbs, fats, and alcohol. Formulated with Gymnema, Turmeric, and probiotics for comprehensive digestive support.

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Powerful Enzyme Formula

Contains 680mg of living enzymes per serving—upgraded from the previous 640mg—featuring Protease, Amylase, and Lipase to support digestion of proteins, carbs, and fats.

Convenient Daily Routine

Take 6 tablets 1-3 times daily with water. The slim aluminum pouch fits easily in bags for on-the-go support after meals.

Quality Assured

Manufactured in a GMP-certified facility in Japan under the supervision of Dr. Hiromi Shintani, a world-renowned gastroenterologist and enzyme expert.

Non-Heat Manufacturing

Proprietary Koji Mold Bio-Fermentation method preserves enzyme activity—unlike heat-processed supplements that may lose effectiveness.

Best For

Those who enjoy sweets, alcohol, and rich foods but want to support their body's natural metabolism and digestive processes.

Trusted Worldwide

Over 22 million units sold globally. Japan's leading enzyme supplement brand with a proven track record since launch.

If you love sweets, desserts, and sugary treats but want to support your body's carbohydrate metabolism naturally

If you enjoy alcohol and social drinking but want enzymatic support to help your body process it more effectively

If you tend to eat rich, oily, or fatty foods and want to support your body's fat metabolism

If you often eat late at night and want enzyme support for nighttime digestion

If you've noticed your metabolism slowing down after your 40s and want to supplement with enzymes that decline with age

If you're looking for a Japanese enzyme supplement backed by scientific research and over 22 million units sold worldwide

If you want a metabolism booster supplement that's preservative-free, gluten-free, and made with 97.9% natural ingredients

If you're seeking a comprehensive enzyme probiotic supplement that combines digestive enzymes with spore-forming lactic acid bacteria

1

Supports Carbohydrate Metabolism

Gymnema Sylvestre, super-increased to 120mg from the previous 8mg, is an herb traditionally used to support carbohydrate metabolism. Combined with Amylase enzyme, this formula helps your body process sugars and starches more efficiently—especially helpful if you love rice, bread, pasta, and sweets.

Traditional herbal ingredient + Digestive enzyme

2

Supports Fat Metabolism

Lipase enzyme supports the breakdown of dietary fats, while newly added Plant Sterol supports healthy lipid balance. This combination is ideal for those who enjoy rich, oily foods and want to support their body's fat processing capabilities.

Enzyme-backed + Newly formulated

3

Supports Alcohol Processing

Turmeric (Ukon), increased to 65mg per serving, has been traditionally used in Japan to support the body after drinking. Combined with the enzyme formula, it helps support your body's natural processing of alcohol—perfect for social occasions.

Traditional Japanese ingredient

4

Supports Gut Health

Contains 30mg of spore-forming lactic acid bacteria that survive heat and stomach acid to reach the intestines alive. These beneficial probiotics support a healthy gut environment, working synergistically with the digestive enzymes.

Probiotic-enhanced formula

Living Enzymes That Actually Work

Most enzyme supplements undergo heat processing that destroys enzyme activity. Night Diet Enzyme GOLD+ uses Shinya Enzyme's proprietary Koji Mold Bio-Fermentation Active Method.

The enzymes are fermented for 48 hours at optimal temperature (around 40°C), then dried at below 48°C using low-temperature air. This non-heat manufacturing process preserves the living, active enzymes.

Three Key Digestive Enzymes

The formula contains three representative enzymes:

Protease - supports protein digestion
Amylase - supports carbohydrate digestion
Lipase - supports fat digestion

These enzymes help break down the three main macronutrients in food.

Enzyme Decline With Age

Research shows that body enzyme levels decline with age. Enzyme production begins decreasing gradually from age 25 and drops rapidly after age 40. This natural decline affects both metabolic enzymes and digestive enzymes, which is why supplementation becomes increasingly important as we age.

Starch Breakdown Demonstration—When Shinya Enzyme is added to a thick starch solution (80% carbohydrate), it becomes watery and thin within just 15 seconds. This visual demonstration shows the active enzymes breaking down carbohydrates.

Consumer Validation: 22 Million Units Sold—Night Diet Enzyme GOLD+ is part of Japan's best-selling enzyme supplement line with over 22 million units sold worldwide (as of June 2023). This remarkable sales figure reflects strong consumer trust.

Expert Supervision—Supervised by Dr. Hiromi Shintani, a world-renowned gastroenterologist who pioneered colonoscopic polypectomy and was recognized by the New England Journal of Medicine.

Quality Manufacturing—Manufactured in a GMP-certified domestic factory in Japan with strict quality control including visual inspection, quality testing, and careful packaging.

A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient Research Highlights

GYMNEMA SYLVESTRE

Gymnema Sylvestre is an herb native to India traditionally used in Ayurvedic medicine. Known as 'Gurmar' (sugar destroyer), it has been studied for its effects on carbohydrate metabolism. The GOLD+ formula contains 120mg per serving—a significant increase from the previous 8mg.

Traditional Ayurvedic use, botanical research

TURMERIC (UKON)

Turmeric has been used for centuries in Japan, particularly for supporting the body after alcohol consumption. The active compound curcumin has been studied for various metabolic support functions. Night Diet Enzyme GOLD+ contains 65mg of turmeric per serving.

Traditional Japanese use, curcumin research

SPORE-FORMING LACTIC ACID BACTERIA

Unlike regular probiotics that may be destroyed by stomach acid, spore-forming lactic acid bacteria have a protective shell that allows them to survive heat and acid. They germinate in the intestines and begin their beneficial activity, supporting gut health.

Probiotic research

The Story

About Brand Story

Shinya Koso Co., Ltd.

Shinya Koso Co., Ltd. produces enzyme supplements developed by Dr. Hiromi Shinya, a world-renowned gastrointestinal endoscopist who pioneered colonoscopic polypectomy in 1968 and has performed over 350,000 endoscopies across the US and Japan. His bestselling book "The Enzyme Factor" sold 3.3 million copies worldwide.
The company's flagship products feature "living enzymes" created through a proprietary non-heat fermentation process developed over 14 years. Combining Japanese fermentation traditions with modern nutritional science, Shinya Koso supplements support Dr. Shinya's core philosophy that enzyme preservation is fundamental to digestive health and longevity.

革新性

Innovation

Shinya Enzyme's proprietary non-heat manufacturing process sets this product apart from competitors. While most enzyme supplements lose activity through heat processing, this formula delivers truly living, active enzymes.

信頼性

Credibility

Over 22 million units sold worldwide, supervised by a world-renowned gastroenterologist, and manufactured in GMP-certified facilities. This track record demonstrates genuine consumer trust and scientific backing.

自然派

Natural Approach

Made with 97.9% natural ingredients, preservative-free, and gluten-free. The formula uses traditional fermented ingredients like koji mold, germinated brown rice, and ancient grains rather than synthetic alternatives.

Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.

Night Diet Enzyme GOLD+ earned its place in our collection because it represents the gold standard in Japanese enzyme supplements. With over two decades of research, a truly innovative manufacturing process, and endorsement by Dr. Shintani, this product delivers what many enzyme supplements only promise—living enzymes that actually work in your body.

Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.

Rigorous Quality Standards

Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.

GMP-Certified Manufacturing

All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.

Centuries of Tradition

Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.

Transparent Sourcing

Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.

Learn more

Take 6 tablets as a single serving, 1 to 3 times daily with water or lukewarm water. For best results, take before or with meals to support digestion. As a dietary supplement, this can be incorporated into your regular eating routine.

Tips for Best Results

Take before or during meals for optimal enzyme activity when food is present
For late-night meals, take right before eating to support nighttime digestion
For alcohol support, take before social drinking occasions
Start with one serving (6 tablets) daily and adjust based on your needs
The slim pouch design fits easily in bags - carry it with you for meals out
Store in a cool, dry place away from direct sunlight

680mg

Living Enzymes

Koji mold fermented enzyme complex (increased from 640mg)

120mg

Gymnema Sylvestre

Supports carbohydrate metabolism (super-increased from 8mg)

65mg

Turmeric (Ukon)

Supports alcohol processing (increased from 60mg)

Ingredients: Koji mold fermented extract powder (maltodextrin, koji mold rice fermented extract) (manufactured in India), papaya processed product (maltodextrin, papaya extract), rice koji powder, Gymnema Sylvestre extract powder, dextrin, isomaltooligosaccharide, long pepper processed product (dextrin, long pepper extract), turmeric powder, koji mold fermented grain extract powder, spore-forming lactic acid bacteria, resistant dextrin, yeast, ginger extract powder, cinnamon powder, black pepper extract / crystalline cellulose, calcium stearate, silicon dioxide, plant sterol, niacin, calcium pantothenate, vitamin B6, vitamin B1, vitamin B2, vitamin B12, (contains soy and sesame)

Allergen Information: Specific Allergens (Required by Law): None. Allergens Equivalent: Soy, Sesame. Gluten: FREE. Preservatives: FREE.

Allergies

Contains soy and sesame. Not suitable for those with allergies to these ingredients. Please check the full ingredient list if you have food allergies.

Natural Variation

Due to the use of natural ingredients, color may vary between batches. This does not affect product quality.

Pregnancy & Nursing

If you are pregnant, nursing, or planning to become pregnant, please consult your healthcare provider before use.

Medications

If you are currently taking prescription medications or are under medical care, please consult your doctor before starting this supplement.

Dosage

The recommended serving is 6 tablets, 1-3 times daily. Do not exceed the recommended daily intake.

Tablet Formulation

To minimize the use of additives (excipients) for binding tablets, the tablets may crumble more easily than conventional supplements. This does not affect product quality.

Discontinue Use

If you experience any adverse reactions, discontinue use immediately.

Storage

Keep in a cool, dry place away from heat and direct sunlight. Keep out of reach of children and pets.

Product Name

Night Diet Enzyme GOLD+ (夜遅いごはんでも GOLD+)

Brand

Shinya Enzyme (新谷酵素)

Contents

180 tablets

Serving Size

6 tablets (1.44g)

Servings Per Container

30 servings

Net Weight

43.2g

Form

Tablet

Country of Origin

Japan

Manufacturing

GMP-certified domestic factory

What is the best metabolism booster supplement for those who eat late at night?

Night Diet Enzyme GOLD+ was specifically designed for people who eat late ("夜遅いごはんでも" literally means "even with late-night meals"). The living enzyme formula supports digestion whenever you eat, including late-night meals.

Take before or with your meal for best results.

Do metabolism booster pills actually work?

Enzyme supplements work by providing digestive enzymes that help break down food. Night Diet Enzyme GOLD+ uses a non-heat manufacturing process to preserve living, active enzymes.

A simple starch breakdown experiment demonstrates these enzymes can liquify starch in just 15 seconds.

What is the fastest metabolism booster?

While no supplement provides instant results, enzyme supplements work immediately on food digestion. Night Diet Enzyme GOLD+ contains Protease, Amylase, and Lipase—the three key enzymes that break down proteins, carbohydrates, and fats.

For overall metabolic benefits, consistent daily use for 4-8 weeks is recommended.

Are there metabolism booster supplements with natural ingredients?

Night Diet Enzyme GOLD+ is made with 97.9% natural ingredients and is preservative-free and gluten-free. The enzyme complex is derived from traditional fermented ingredients including koji mold, germinated brown rice, and ancient grains—not synthetic sources.

What makes Japanese enzyme supplements different?

Japanese enzyme supplements like Night Diet Enzyme GOLD+ use traditional koji mold fermentation, a technique refined over centuries in Japanese food culture.

The proprietary manufacturing process ferments ingredients for 48 hours at optimal temperature, then dries below 48°C to preserve enzyme activity.

Can enzyme supplements help with digestion after drinking alcohol?

Night Diet Enzyme GOLD+ contains 65mg of Turmeric (Ukon), traditionally used in Japan to support the body after drinking. Combined with the digestive enzyme complex, it provides comprehensive support for social occasions.

Take before drinking for best results.

What enzyme supplements do nutritionists recommend?

Nutritionists typically recommend enzyme supplements with clearly disclosed ingredient amounts and quality certifications. Night Diet Enzyme GOLD+ lists exact amounts per serving, is manufactured in GMP-certified facilities, and is supervised by Dr. Hiromi Shintani, a world-renowned gastroenterologist.

Is Night Diet Enzyme GOLD+ suitable for vegetarians?

The formula is gluten-free and preservative-free but contains some ingredients derived from natural sources. Please check the full ingredient list for your dietary requirements.

The primary fermentation base uses plant-based ingredients like germinated brown rice and ancient grains.

How is GOLD+ different from the regular Night Diet Enzyme?

GOLD+ is the upgraded formula with increased enzyme content (680mg vs 640mg), super-increased Gymnema Sylvestre (120mg vs 8mg), increased Turmeric, increased probiotics, plus new additions of Long Pepper and Plant Sterol—all at a lower price than the previous GOLD version.

Where can I buy authentic Japanese enzyme supplements?

Authentic Night Diet Enzyme GOLD+ is available at Naturacare.jp, your trusted source for genuine Japanese health supplements. We ship directly from Japan with authenticity guaranteed.

Beware of counterfeit products on unauthorized marketplaces.

Rediscovered why I loved this

I bought this years ago after reading about the brand, then stopped taking it for a while. Recently picked it back up and was reminded how effective it actually feels. There's something about the enzyme formula that seems to work—you can sense the difference in how your body processes things overnight. Definitely recommending it again.

Good supplement, just hard to measure

About six tablets before bed is easy enough to manage. The product itself is well-made and I do feel less bloated in the mornings compared to before I started. My only reservation is that metabolism effects are inherently difficult to measure, so I cannot be completely certain how much credit goes to this supplement versus diet changes.

My body responds to this one

This feels legitimately different from other metabolism supplements I've tried. The effect is clear and consistent.

Noticeable difference in hunger patterns

Started taking this after a friend's recommendation and noticed my appetite behaves differently. The effect feels real and measurable.

The bacteria feel like they're doing their job

Taking six tablets before bed became part of my routine, and there's something distinctive about how this product makes you feel. Unlike absorption-blocking supplements I've tried, this one creates a real sensation—you can almost feel the bacteria metabolizing the sugars you ate during the day. Within a couple hours of taking it, hunger returns, which suggests active metabolism happening. The formulation with proper bacterial temperature management seems to make a genuine difference. I've gone back and forth on taking it, but every time I restart, I'm reminded of the noticeable effect it produces.

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Night Diet Enzyme GOLD+: Japanese Metabolism Booster Supplement with 680 Living Enzymes