Key Takeaways
Dual Functional Ingredients
Japan's first functional food combining L-Ornithine HCl (500mg) and Crocin (7.5mg) to address both sleep quality and morning fatigue.
Simple Daily Routine
Take 4 tablets before bed with water. One pouch provides a full 30-day supply for consistent daily support.
Rigorous Quality Control
100% in-house development from ingredient selection through research in FANCL's integrated facility. Hundreds of quality tests performed.
Clinically Studied Ingredients
Both ingredients backed by systematic reviews. L-Ornithine shown to improve sleep quality in 5-week clinical study.
Best For
Busy professionals in their 30s-50s who feel tired upon waking, experience lingering fatigue, or struggle to start mornings refreshed.
Consumer Validated
83% satisfaction rate and 85% intention to continue among busy users in their 40s (FANCL survey, November 2020).
Is This Right For You?
Recommended For
This ornithine supplement is designed for those seeking natural support to improve sleep quality and reduce morning fatigue.
If you're waking up feeling tired despite getting enough sleep hours
If you've been struggling with lingering fatigue that affects your productivity at work
If you're in your 30s-50s juggling demanding work schedules and family responsibilities
If you want to support your body's natural sleep recovery processes with a non-pharmaceutical approach
If you're looking for a Japanese functional food with clinically studied ingredients
If you experience fatigue during work hours (42% of people report this issue)
If you want to establish a better nighttime routine that helps you wake up refreshed
If you value transparency and quality assurance from a trusted Japanese brand with 100% in-house development
Why It Works
Benefits
FANCL Sleep & Fatigue Care delivers dual-action support through carefully selected functional ingredients.
Improves Sleep Quality
L-Ornithine HCl has been reported to improve sleep quality, specifically the sensation of having slept longer. In clinical studies, participants taking L-Ornithine HCl for 5 weeks showed significant improvement in sleep duration scores compared to placebo. This supports better rest without drowsiness the next day.
Systematic Review CompletedReduces Morning Fatigue
Crocin, derived from gardenia fruit, has been reported to reduce fatigue upon waking. In a randomized, double-blind crossover study with adults aged 35-60, participants taking 7.5mg of crocin for 2 weeks showed improved fatigue recovery scores compared to control group.
Clinically ValidatedSupports Better Morning Awakening
The combination of improved sleep quality and reduced fatigue helps support a more refreshed feeling upon waking. L-Ornithine supports better mood upon awakening, helping you start your day with more energy and clarity.
Research-backed IngredientsComprehensive Vitamin B Support
Includes Vitamin B1 (15mg), B2 (6mg), and B6 (10mg) plus Inositol (40mg) to support energy metabolism. These essential B-vitamins complement the functional ingredients for overall wellness support throughout the day.
Nutritional SupportThe Science
How It Works
Understanding how FANCL Sleep & Fatigue Care supports your body's natural sleep and recovery processes.
L-Ornithine HCl for Sleep Quality
Research shows it improves:
- The sensation of sleeping longer
- Better mood upon waking
Crocin for Fatigue Relief
It has been reported to reduce fatigue upon waking. The systematic review of crocin research confirms its effects on morning fatigue reduction.
Sleep + Fatigue Recovery Cycle
Quality sleep is essential for fatigue relief. This supplement addresses both factors: improving sleep quality AND reducing morning fatigue.
The Science
Research & Evidence
What clinical research tells us about the key functional ingredients in this ornithine supplement.
L-Ornithine Sleep Quality Study—A randomized, placebo-controlled study with 24 participants (ages 40-64) taking L-Ornithine HCl 500mg for 8 weeks showed significant improvement in sleep duration scores at week 5 (p<0.05). Source: Nutrition Journal, 2014;13:53
Crocin Fatigue Relief Study—A randomized, double-blind crossover study with 24 healthy adults (ages 35-60) taking crocin 7.5mg for 2 weeks showed improved fatigue recovery scores upon waking (p<0.05). Source: Complementary Therapies in Medicine, 2018;41:47-51
Fatigue Prevalence Statistics—90% of people experience fatigue 2+ days per week. The most common time to feel fatigued is upon waking (57.7%), followed by returning home from work (50.3%). Source: FANCL survey, October 2020 (n=600)
Customer Satisfaction Data—Among busy men and women in their 40s who tried the product: 83% overall satisfaction rate and 85% intention to continue use. Source: FANCL monitor survey, November 2020 (n=68)
A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.
Ingredient Research Highlights
L-ORNITHINE HCL
L-Ornithine is an amino acid that has been studied for its effects on sleep quality. Research indicates that L-Ornithine supplementation may improve subjective sleep quality, particularly the sensation of having slept longer, and support better mood upon waking.
Nutrition Journal clinical studyCROCIN (CROCETIN)
Crocin is a carotenoid pigment found in gardenia fruit and saffron. Studies suggest crocin supplementation may help reduce fatigue upon waking by supporting the body's natural recovery processes during sleep.
Complementary medicine clinical researchCONSUMER VALIDATION
Product developed by FANCL, a trusted Japanese pharmaceutical and wellness brand. Survey data shows 83% satisfaction rate among target users. The dual-ingredient formulation is Japan's first of its kind among functional foods.
FANCL consumer surveysThe Story
About Brand Story
FANCL Corporation
Expanding into supplements in 1994, FANCL helped popularize the "supplement" concept in Japan and now holds top market share in functional food supplements. The company operates its own research institute and manufacturing facilities, ensuring quality from development through production. Now part of the Kirin Holdings group, FANCL continues its mission of "Honest Quality" across beauty and wellness.
Our Curation Process
Why We Selected This Product
Every product at Naturacare undergoes rigorous evaluation before joining our collection.
革新性
Innovation
Japan's first functional food to combine L-Ornithine HCl and Crocin in a single formulation. This dual-approach addresses both sleep quality and morning fatigue - two interconnected wellness concerns.
品質
Quality Assurance
FANCL's 100% in-house development means no external outsourcing - from ingredient sourcing through research and manufacturing. Hundreds of quality tests are performed, with strict safety standards starting from raw materials.
信頼性
Reliability
Backed by systematic reviews of both functional ingredients. Registered as functional food G58 with Japan's Consumer Affairs Agency, meeting strict evidence standards for health claims.
Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.
We selected FANCL Sleep & Fatigue Care because it represents rigorous Japanese quality standards combined with clinically-studied ingredients. For those seeking a non-pharmaceutical approach to better sleep and reduced morning fatigue.
Why Japan
The Japanese Advantage
Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.
Rigorous Quality Standards
Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.
GMP-Certified Manufacturing
All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.
Centuries of Tradition
Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.
Transparent Sourcing
Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.
Directions
How to Use
Simple nightly routine for optimal results.
One pouch provides a complete 30-day supply.
Consistency is key - take at the same time each night to establish a routine.
Tips for Best Results
- Take before bedtime for optimal sleep quality support
- Maintain consistent daily intake for best results
- Store in a cool, dry place away from heat and direct sunlight
- Urine may temporarily appear yellow due to Vitamin B2 - this is normal
- Close the pouch securely after opening and use promptly
- Do not consume the desiccant packet inside
What's Inside
Ingredients
Transparent formulation with functional and supporting ingredients.
L-Ornithine HCl
Functional ingredient for sleep quality improvement
Crocin (Crocetin)
Functional ingredient for fatigue reduction upon waking
Inositol
Vitamin-like compound for wellness support
Ingredients: L-Ornithine HCl (manufactured in USA), Starch, Cellulose, Sucrose ester, Inositol, Hydroxypropyl cellulose, Silicon dioxide, Vitamin B1, Gardenia pigment, Magnesium stearate, Vitamin B6, Vitamin B2, Shellac
Allergen Information: Contains: None of the 28 designated allergens. Free From: Major allergens (eggs, milk, wheat, etc.)
Important Information
Safety & Precautions
Please read before use.
Allergies
Check ingredients list if you have food allergies. This product does not contain any of the 28 designated allergens in Japan.
Pregnancy & Nursing
Not recommended for pregnant or nursing women. Please consult your healthcare provider.
Children
Not recommended for children. This product is intended for adults.
Medications
If you are taking medications or have health conditions, consult your healthcare provider before use.
Dosage
The recommended daily intake is 4 tablets. Do not exceed the recommended amount. If you experience any discomfort, reduce intake or discontinue use.
Discontinue Use
If you experience any adverse effects or feel unwell, stop taking immediately and consult a healthcare professional.
Storage
Store in a cool, dry place away from direct sunlight and heat. Keep out of reach of infants. Close pouch securely after opening.
Disclaimer
This is a functional food, not a medicine. It is not intended to diagnose, treat, cure, or prevent any disease. Maintain a balanced diet.
Details
Product Specifications
Questions
Frequently Asked Questions
Research shows it may improve the sensation of sleeping longer and support better mood upon waking, making it beneficial for those experiencing sleep-related fatigue.
In a double-blind study, participants taking 500mg daily for 5 weeks showed significant improvement in sleep duration scores compared to placebo.
Research shows crocin may help reduce fatigue upon waking, complementing ornithine's sleep quality benefits for comprehensive sleep and fatigue support.
Check the ingredients if you have any food allergies.
FANCL recommends consistent daily use for best results. Customer surveys show 83% satisfaction among users in their 40s.
FANCL's 100% in-house development ensures quality control from ingredient selection through manufacturing.
This product contains Vitamins B1, B2, B6, and Inositol, which may overlap with other supplements.
If you experience any discomfort, reduce intake or discontinue use and consult a healthcare professional.
We verify all products for authenticity and provide English-language support for international customers seeking genuine Japanese health supplements.
This ornithine supplement addresses both sleep quality and morning fatigue for better recovery.