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SPIC Corporation

Lypo-C: Japan's Premium High-Absorption Vitamin C Supplement

Lypo-C: Japan's Premium High-Absorption Vitamin C Supplement

Japan's first domestically manufactured liposome vitamin C delivers 1000mg per packet with enhanced absorption. Liquid liposome technology ensures vitamin C reaches where your body needs it most.
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Regular price $74.45 USD
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Key Takeaways

Advanced Liposome Technology

Japan's first domestically manufactured liposome vitamin C using patented technology that creates uniform 100nm nano-size capsules for enhanced absorption.

High-Dose Convenience

Each individual packet delivers 1000mg of high-quality vitamin C from Scotland (DSM Q-C), making daily supplementation simple and portable.

Pure Formulation

Free from sweeteners, colorings, fragrances, and preservatives. Contains only essential ingredients needed for effective vitamin C delivery.

Japanese Quality Manufacturing

Produced in GMP-certified facilities in Japan with strict quality control, representing decades of research into liposome technology.

Best For

Those seeking maximum vitamin C absorption for skin health support, daily wellness, and preparation for demanding days or sun exposure.

Award-Winning Recognition

Winner of 9 Best Cosmetic Awards (2023-2024) and ranked #1 on Rakuten in the Vitamin C category with 464+ reviews.

Why It Works

Benefits

Lypo-C delivers vitamin C through innovative liposome technology developed in Japan.

1

Enhanced Absorption Through Liposome Technology

Unlike regular vitamin C supplements that have limited absorption due to water solubility, Lypo-C encapsulates vitamin C in phospholipid capsules similar to your cell membranes. This liposome technology helps protect vitamin C through digestion and supports delivery to where your body needs it, maximizing the benefits of each 1000mg dose.

Patented Japanese technology
2

Supports Skin Health & Radiance

Vitamin C is essential for collagen synthesis, which supports skin structure and appearance. Many users take Lypo-C before sun exposure and as aftercare to support their skin from within. The high-absorption formula helps ensure your body receives the vitamin C it needs for natural beauty support.

Essential nutrient for collagen
3

Daily Wellness & Vitality Support

Vitamin C is rapidly consumed during stress, busy schedules, and physical activity. Modern lifestyles often deplete this essential nutrient faster than we can replenish it through diet alone. Lypo-C provides convenient, high-dose vitamin C support to help maintain daily wellness and vitality.

Essential daily nutrient
4

Pure, Additive-Free Formula

Lypo-C contains no sweeteners, colorings, fragrances, or preservatives. The formula focuses solely on delivering effective vitamin C without unnecessary additives. The resulting sea-water-like taste comes from the sodium used to stabilize the liposomes - a sign of its pure, functional formulation.

No unnecessary additives

The Science

How It Works

Understanding Lypo-C's innovative liposome technology.

Liposome Encapsulation Technology

Liposome Encapsulation Technology

Vitamin C is water-soluble and has limited absorption in the body - much of what you consume is simply excreted.

Lypo-C addresses this by encapsulating vitamin C in liposomes: tiny capsules made of phospholipids (the same material as cell membranes).

This liposome technology helps protect the vitamin C and supports its delivery into cells more effectively than conventional supplements.
Liquid Form Preserves Liposome Integrity

Liquid Form Preserves Liposome Integrity

Lypo-C remains in liquid form specifically to preserve liposome integrity.

When liposomes are dried into powder form, many capsules break down and their uniform size becomes compromised.

Lypo-C's patented stabilization technology allows liquid liposomes to be packaged in sachets while maintaining their approximately 100nm uniform nano-size - the optimal size for absorption.

The Science

Research & Evidence

What makes Lypo-C different from conventional vitamin C supplements.

Japan's First Domestically Manufactured Liposome Vitamin C

Japan's First Domestically Manufactured Liposome Vitamin C—Lypo-C was developed with the goal of creating a high-quality liposome vitamin C supplement manufactured in Japan. In January 2015, it became the first liposome vitamin C supplement to be manufactured domestically in Japan.

Award-Winning Recognition

Award-Winning Recognition—Lypo-C has received 9 Best Cosmetic Awards in the supplement category across fashion, beauty, and women's magazines in 2023-2024. The product is also recommended by the Japan Society for Integrative Medicine.

Advanced Liposome Technology

Advanced Liposome Technology—Secret 1 | Liquid Liposomes A raw state without alteration Lypo-C is the only domestically manufactured product with stabilization technology capable of packaging vitamin C liposomes in liquid form in pouches. Secret 2 | Nearly Uniform Size Efficiently delivers high concentration! Most liposomes are stable at an ultra-small size of approximately 100nm. Through stabilization technology that prevents them from growing larger over time, you can supplement with high-quality liposomes.

A Note on Evidence: We present research on ingredients, not specific product claims. Individual results may vary. This supplement is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient Research Highlights

LIPOSOME TECHNOLOGY

Liposome encapsulation technology has been studied for its potential to enhance nutrient delivery. Liposomes are phospholipid vesicles that can encapsulate water-soluble nutrients, potentially protecting them during digestion and supporting cellular uptake.

Scientific research on liposome delivery systems
VITAMIN C (ASCORBIC ACID)

Vitamin C is an essential nutrient that the human body cannot produce on its own. It supports collagen synthesis, antioxidant function, and immune health. Conventional vitamin C supplements have limited absorption, with excess amounts being excreted.

Nutritional biochemistry research
DSM Q-C VITAMIN C

Lypo-C uses Q-C vitamin C manufactured by DSM in Scotland. This pharmaceutical-grade vitamin C meets strict quality standards including traceability and non-GMO verification.

DSM quality specifications

About Brand Story

SPIC Corporation

SPIC Corporation

SPIC Corporation is a Japanese health supplement company based in Kamakura. In 2007, Dr. Atsuo Yanagisawa, a leading IV therapy authority, introduced high-dose vitamin C technology from the United States and partnered with SPIC to create a convenient, high-quality liposomal supplement for home use.

In 2014, SPIC developed its proprietary Lipo-Capsule Technology, and in January 2015 launched Lypo-Capsule Vitamin C—Japan's first domestically manufactured liposomal vitamin C supplement. In 2023, the company expanded with Lypo-Capsule Vitamin C+D, continuing its mission to deliver essential nutrients deep into the body.

Our Curation Process

Why We Selected This Product

Every product at Naturacare undergoes rigorous evaluation before joining our collection.

革新性

Innovation

Japan's first domestically manufactured liposome vitamin C, representing genuine innovation in supplement technology rather than following trends.

本物

Authenticity

Born from medical expertise - developed based on high-dose IV vitamin C therapy knowledge, with input from 60 medical and beauty professionals.

純粋

Purity

No sweeteners, colorings, fragrances, or preservatives. Only essential ingredients for effective vitamin C delivery, even if it means a less palatable taste.

Our Promise: We don't just import popular Japanese supplements - we investigate each product's formulation, manufacturing standards, and real-world reputation in Japan.

Lypo-C represents Japanese dedication to quality and innovation. We selected it because it offers a genuinely differentiated approach to vitamin C supplementation - not just another vitamin C tablet, but advanced liposome technology that addresses the fundamental challenge of absorption.

Why Japan

The Japanese Advantage

Japan's supplement industry operates under some of the world's strictest quality standards. Combined with a cultural dedication to craftsmanship and centuries of wellness traditions, Japanese supplements represent a level of quality that's difficult to find elsewhere.

Rigorous Quality Standards

Japanese regulations require comprehensive testing at every stage of production, with standards that often exceed international requirements.

GMP-Certified Manufacturing

All our products come from facilities that meet Japan's strict GMP (Good Manufacturing Practice) certification requirements.

Centuries of Tradition

Many Japanese supplements draw on ingredients and formulations refined over generations, combining ancient wisdom with modern science.

Transparent Sourcing

Japanese manufacturers maintain complete traceability, so you know exactly where every ingredient comes from.

Directions

How to Use

Simple daily routine for optimal results.

Take 1-3 packets daily as a dietary supplement.

Best taken on an empty stomach, such as before meals.

Can be consumed directly from the packet or mixed with water or fruit juice.

Do not mix with hot water above 60C (140F) or oil-based beverages.

Tips for Best Results

  • Take on an empty stomach for best absorption (before meals is ideal)
  • For sun care: take before going outdoors and after returning
  • For special occasions: start taking 3 days before important events
  • For active lifestyles: take before bath time or before bed after a busy day
  • Mix with vegetable juice for a morning wellness routine
  • Store in a cool, dry place; refrigeration recommended after opening

What's Inside

Ingredients

Pure formulation with essential ingredients only.

1,000mg

Vitamin C

High-quality ascorbic acid from Scotland (DSM Q-C) per packet

100nm

Liposome Size

Uniform nano-size phospholipid capsules for optimal absorption

0

Additives

No sweeteners, colorings, fragrances, or preservatives

Ingredients: Vitamin C (manufactured in UK), Lecithin (from soybean), Alcohol, Sodium Citrate, Citric Acid

Allergen Information: Contains: Soy (lecithin is derived from soybean). Does NOT contain: Sweeteners, colorings, fragrances, preservatives.

Important Information

Safety & Precautions

Please read before use.

Allergies

Contains soy-derived lecithin. Not suitable for those with soy allergies.

Pregnancy & Nursing

Consult your healthcare provider before use if you are pregnant, nursing, or planning to become pregnant.

Medications

If you take prescription medications, consult your doctor before starting this supplement.

Dosage

The recommended daily amount is 1-3 packets. Do not exceed the recommended daily amount.

Usage Notes

Do not mix with hot water above 60C (140F) as heat may affect the liposomes. Do not mix with oil-based beverages. The product has a sea-water-like taste due to sodium used for liposome stabilization.

Discontinue Use

If you experience any adverse effects, discontinue use and consult a healthcare professional.

Storage

Keep in a cool, dry place away from direct sunlight and heat. After opening individual packet, consume immediately.

Disclaimer

This is a dietary supplement, not a medicine. It supports wellness but does not treat, cure, or prevent any disease.

Details

Product Specifications

Product Name
Lypo-C Vitamin C (リポ・カプセル ビタミンC)
Brand
SPIC
Contents
30 packets
Serving Size
1 packet (6.176g)
Servings Per Container
30 servings
Net Weight
185.28g (6.176g x 30 packets)
Form
Liquid in individual sachets
Country of Origin
Japan
Manufacturing
SPIC Corporation (GMP-certified)

Questions

Frequently Asked Questions

Japan has a strong wellness culture and vitamin C is valued for its role in skin health and daily vitality.

Japanese consumers prioritize quality and absorption, driving innovation in supplement technology like liposome encapsulation. This demand led to products like Lypo-C, which focuses on delivering vitamin C more effectively.
Lypo-C by SPIC is one of Japan's most acclaimed vitamin C japan supplements, ranking #1 on Rakuten in the Vitamin C category and winning 9 Best Cosmetic Awards.

It's known for being Japan's first domestically manufactured liposome vitamin C, developed with input from medical professionals.
Japanese vitamin C supplements often emphasize quality manufacturing and innovative delivery technologies.

Lypo-C represents this approach with liposome technology that encapsulates vitamin C in phospholipid capsules for enhanced absorption, unlike conventional tablets or powders that have limited absorption due to vitamin C's water-soluble nature.
Regular vitamin C is water-soluble and much is simply excreted by the body before absorption.

Liposome technology encapsulates vitamin C in tiny phospholipid capsules (similar to cell membranes) that help protect it through digestion and support delivery into cells more effectively.
Look for liposome technology for better absorption, transparent ingredient sourcing (like Lypo-C's use of DSM Q-C from Scotland), domestic Japanese manufacturing in GMP facilities, no unnecessary additives, and liquid form which preserves liposome integrity better than powders.
Taking Lypo-C on an empty stomach (such as before meals) is recommended for optimal absorption.

Many users take it before sun exposure for skin support, 3 days before important events for preparation, or before bed after active days for recovery and wellness support.
Lypo-C has a distinctive sea-water-like taste with some bitterness, which is intentional.

The company does not add sweeteners, flavorings, or colorings - focusing only on ingredients necessary for effective vitamin C delivery. Many users mix it with vegetable juice or fruit juice if preferred.
Each Lypo-C packet contains 1,000mg of vitamin C.

The recommended daily intake is 1-3 packets depending on your needs. The vitamin C used is pharmaceutical-grade Q-C manufactured by DSM in Scotland, meeting strict quality and non-GMO standards.
  • 5 stars: 18 (60%)
  • 4 stars: 8 (27%)
  • 3 stars: 2 (7%)
  • 2 stars: 0 (0%)
  • 1 star: 2 (7%)
H
Hyun-seo Lee
Flavor too harsh to tolerate daily

The flavor is genuinely unbearable—like petroleum mixed with salt. I couldn't persist with daily doses no matter how much I wanted the vitamin C benefits.

V
Valentina Romano
Flavor improves with consistent use

The taste seemed strange at first, but I've grown accustomed to it over time. I'm a repeat buyer now and the results keep me coming back.

V
Vivian Loh
Unusual liquid gel flavor profile

The taste is distinctly oily and thick—nothing like standard vitamin C powder. It's more salty than sour, with an odd consistency. Some people will struggle with this, and a sample size option would be helpful before committing to a full box.

D
Daria Kuznetsova
Energy boost and glowing skin

My hair and nails strengthened within a month, and I wake up genuinely refreshed now. The taste is unusual but manageable when chilled.

L
Lukas Schmidt
Immune support and wellness boost

Great for cold prevention and general wellness support.

M
Maria Lourdes Garcia
Results are exceptional despite flavor

The taste isn't pleasant, but the results are undeniable. I tried switching to other products once, but the effects weren't comparable, so I came back. When it comes to skin clarity and wellness, this formula delivers what others don't.

L
Lily Crawford
Skin transformation worth the taste challenge

The taste is genuinely awful—like thick petroleum with a salty, pre-vomit edge—but I've learned to work around it by mixing each packet into tomato juice, which completely masks the flavor. Within three weeks, my skin became noticeably brighter and more transparent, and the persistent acne breakouts I'd struggled with for months simply stopped. My nails grew stronger too, and I noticed I had more alertness in the mornings. The liposomal format absorbs incredibly fast, which I can feel working. When I ran out and took a break for six weeks, my skin clarity deteriorated within two months, which proved to me this supplement is genuinely effective. Yes, the taste is a real hurdle, but the results are undeniable.

P
Phoebe Lawson
Compared unfavorably to competing liposomal brands

Compared to other liposomal vitamin C products, my skin showed noticeably better results with those alternatives. The efficiency of this formula's absorption didn't translate to the same visible improvements I experienced elsewhere. The individual packets are practical and easy to consume, but the actual skin impact wasn't what I'd hoped for based on the liposomal technology promises.

B
Blake Russell
Unpleasant taste outweighs benefits

The flavor is genuinely difficult to tolerate—it tastes like liquid vitamin mixed with a salty, pre-vomit sensation. Even knowing others report benefits, I can't maintain daily intake because the taste makes it impossible. Standard vitamin C tablets would be far more practical for someone like me.

H
Hugo Thornton
No taste when consumed correctly

I expected the worst based on reviews, but using the right technique—holding water in your mouth first, pinching your nose, then swallowing—the taste disappeared completely.

A
Amelie Petit
Tomato juice masks the flavor completely

Mix this into tomato juice and the taste vanishes entirely. After stopping use for about six weeks, my skin condition noticeably declined, which proved how much this product was actually working. I'm back on it full-time now.

D
Divya Sharma
Quick effects, quick flavor adaptation

Yes, the taste is challenging initially, but it fades in seconds. The skin brightening and energy boost make the momentary discomfort worthwhile—beauty truly does require a little sacrifice.

M
Marcus Ross
Effective but requires proper technique

The flavor concentrates at the back of the throat, so drinking method matters. Pinch your nose, swallow quickly with water, then rinse your mouth—this eliminates the unpleasant aftertaste. On my third box now.

N
Nurul Huda
Solid results, easy routine

The product quality is good—it works as intended for skin health and general wellness. My one note is that the taste takes some getting used to, but the results justify sticking with it.

T
Trevor Simmons
High effectiveness, undeniable impact

The results are strong enough that I can't stop using this. Once you see the skin clarity improvements, going without feels like stepping backward.

T
Thomas Blackwood
Skin transformation with manageable flavor

The flavor is unusual—somewhat citrus but with an underlying salted edge that caught me off guard initially. My strategy is to follow consumption with water, then vegetable juice, which neutralizes any lingering taste. After consistent use, my skin clarity and brightness improved noticeably, and mornings feel more refreshed. The individual packets are hygienic and portable, making daily intake simple even when traveling. I notice the difference when I skip doses, so the formula is clearly effective.

P
Philippe Gauthier
Works well for skin, taste requires commitment

After several months of daily use, I've noticed genuine improvements in my skin clarity and brightness. The liposomal vitamin C format seems more effective than standard supplements I've tried before. The only downside is the taste—I have to pinch my nose and chase it with water each time. But the visible results make the daily routine worthwhile.

G
Grace Chua
Results visible, taste requires strategy

The flavor has a subtle citrus quality mixed with something distinctly salty and oily—it's unconventional but manageable with the right approach. Chase it with water and juice to eliminate any lingering taste. My skin's transparency and overall clarity have genuinely improved with continued use, and my energy upon waking is noticeably sharper. The liposomal format absorbs efficiently, and the individual packets are clean and travel-friendly. The actual skin and wellness improvements justify the commitment for me.

K
Katarina Novak
Taste takes getting used to

Only two weeks in, so I haven't noticed major effects yet. I see complaints about the flavor online, but I've adjusted to it. If you expect typical sour vitamin C, you'll be surprised—think of it as an unusual broth instead, and it becomes less jarring.

E
Eleonora Marchetti
Chilling transforms the experience

The taste ranks among the more tolerable liposomal formats I've tried. Chilling it thoroughly in the refrigerator really neutralizes the unpleasant notes. Many competing products add sweeteners or undergo strange processing, so the pure formula here feels worthwhile. I mix mine into vegetable juice on most days, and the salty note actually complements it well. The fact that it contains no artificial additives is a genuine advantage—you're getting the active ingredient without the usual fillers. After a month of daily use, I'm noticing my skin appears brighter and more translucent than before. The small packet size (just two squeezes) is convenient, and the quick absorption is noticeable.

M
Mateo Fernandez
Brilliant results, revolting flavor

Tastes like liquid oil with a salty bite, but the skin brightening and breakout prevention are absolutely worth powering through.

H
Hugo Bernard
Noticeable skin improvement

After several weeks of daily use, my skin tone has visibly brightened and feels healthier overall. The liposomal format seems to absorb well, and I've noticed improvements in my complexion that other vitamin C supplements never delivered. Very happy with this product.

M
Mariam Jallow
Mix it into your favorite juice

I pour one packet into vegetable juice after my evening shower, and it blends seamlessly. My skin has noticeably brightened over the past month. The salty undertone works surprisingly well with vegetable-based drinks. Taking this consistently has become part of my daily wellness routine.

H
Hannah Gray
Tastes bad and no visible benefit

I was drawn by the liposomal format's claim of superior absorption and longer retention in the body compared to standard vitamin C. However, after a full year of taking two packets daily, my skin shows no meaningful improvement despite already prioritizing vitamin C intake through other sources. The terrible taste makes each serving an ordeal.

V
Vivienne Leclerc
Skin transformation within weeks

Three months into daily use, my skin has completely transformed. Acne breakouts that plagued me for years have stopped, and my complexion is noticeably clearer and brighter. My nails grow faster and stronger than ever before, and my hair feels healthier overall. I also wake up with much more alertness and morning freshness—it's become an essential part of my routine. The liposomal format is genuinely efficient; I feel the effects quickly after taking it. What really convinced me of its efficacy is what happened when I ran out for six weeks: my skin deteriorated noticeably, acne returned, and I felt less energized. I immediately reordered and within two weeks, the improvements came roaring back. The tiny packet size is deceptive—the concentrated formula packs serious potency. Yes, the taste is unconventional (salty, oily, nothing like typical vitamin C), but I've learned to chase it with water or mix it into tomato juice. No lingering aftertaste if you rinse immediately. The complete absence of sweeteners, coloring, or preservatives means you're consuming pure liposomal vitamin C, which I believe directly correlates to the visible results. This is a legitimate skin-health tool, not a placebo.

P
Padma Lakshmi
Tastes better than expected

Everyone online warned me about the flavor, so I braced myself. Honestly, it's nowhere near as bad as the reviews suggest. It's basically flavorless with a faint citrus undertone—mild and manageable. I can drink it straight without water, and I'm planning to continue taking it regularly. The small serving size means just a couple of squeezes and you're done. I'm still waiting to see the full effects, but the taste barrier is far lower than people claim.

S
Siti Nurhaliza
Skin clearing within days

My skin breakouts have genuinely stopped since I started this.

A
Abdul Rahman
Noticeable skin brightness

Within the first month, my skin became visibly brighter and more radiant. I take it regularly for that effect alone.

Z
Zahra Karimi
Check the packet count carefully

Make sure you're ordering the correct box size to avoid confusion.

G
Gregory Cook
Adjustment period is real

The flavor is genuinely challenging at first—oily and salty, like petroleum mixed with salt. I expected to quit after the first packet. But I committed to drinking it with water beforehand and rinsing immediately after. After two weeks, my taste buds adapted. Now it barely registers as unpleasant. My skin has brightened considerably, and my nails are noticeably stronger. The trick is not to overthink the taste; chase it with liquid and move on. No lingering aftertaste if you rinse. The concentration of liposomal vitamin C is impressive—you feel the absorption is genuine, not like typical powders.